WebWe present CgA and gastrin data in relation to ppi therapy and withdrawal for this patient. In order to see if this was an isolated incident, we audited all laboratory requests for CgA/gastrin in a two-year period and monitored those that provided details of ppi treatment/withdrawal. ... Keywords: Chromogranin A, proton pump inhibitors, gastrin ... WebDec 29, 2015 · As in the present case, Jianu et al. describe two patients who had been taking PPIs for 12–13 years who had solitary tumors in the oxyntic mucosa observed on routine EGD, accompanied by elevated serum concentrations of gastrin and chromogranin during PPI therapy. Pathologic findings were consistent with “well-differentiated” NETs in …
Zollinger-Ellison syndrome - Diagnosis and treatment - Mayo Clinic
WebA well-known side effect of PPI therapy that may cause serious differential diagnostic problems is the elevation of serum chromogranin A (CgA). Objective: We report a case … WebBackground: The neuroendocrine marker, chromogranin A (CgA) increases during medium- or long-term proton-pump inhibitor (PPI) treatment. Aims: To analyze the effect … simonmed ironwood
Effect of Proton-Pump Inhibitor Therapy on Serum …
WebSome PPI users develop fundic gland polyps. The purpose of this study was to determine whether patients developing fundic gland polyps have a more pronounced gastric hypoacidity, hypergastrinemia or increased serum chromogranin A (CgA), which is an enterochromaffin-like (ECL) cell marker. WebJan 19, 2024 · Neuroendocrine tumors (NETs) throughout the body are the focus of much current interest. Most occur in the gastrointestinal tract and have shown a major increase in incidence over the past 30 years, roughly paralleling the world-wide increase in the use of proton pump inhibitor (PPI) drugs. The greatest rise has occurred in gastric carcinoids … WebSep 27, 2024 · PPIs are generally well tolerated. The more common side effects reported with their use include: A headache. Fever. Gastrointestinal effects (such as abdominal pain, constipation, diarrhea, flatulence, nausea, or vomiting) Light-headedness. Magnesium or vitamin B12 deficiency (usually only with long-term administration) Rash. simonmed in sun city az